An azimuthally resolved study of the cold front in Abell 3667

The microphysical properties, such as effective viscosity and conductivity, of the weakly magnetized intergalactic plasma are not yet well known. We investigate the constraints that can be placed by an azimuthally resolved study of the cold front in Abell 3667 using similar to 500 ks archival Chandra data. We find that the radius of the interface fluctuates with position angle and the morphology of the interface is strikingly similar to recent numerical simulations of inviscid gas-stripping. We find multiple edges in the surface brightness profiles across the cold front as well as azimuthal variations, which are consistent with the presence of Kelvin-Helmholtz instabilities (KHIs) developing along the cold front. They indicate that the characteristic length-scale of KHI rolls is around 20-80 kpc. This is the first observational indication of developing KHIs along a merger cold front in a galaxy cluster. Based on the KHI scenario, we estimated the upper limit of the intracluster medium effective viscosity. The estimated value of mu less than or similar to 200 g cm(-1) s(-1) is at most 5 per cent of the isotropic Spitzer-like viscosity. The observed apparent mixing towards the outer edges away from the tip of the front provides an additional evidence for suppressed viscosity

Serendipitous discovery of an extended X-ray jet without a radio counterpart in a high-redshift quasar

A recent Chandra observation of the nearby galaxy cluster Abell 585 has led to the discovery of an extended X-ray jet associated with the high-redshift background quasar B3 0727+409, a luminous radio source at redshift z=2.5. This is one of only few examples of high-redshift X-ray jets known to date. It has a clear extension of about 12", corresponding to a projected length of ~100 kpc, with a possible hot spot located 35" from the quasar. The archival high resolution VLA maps surprisingly reveal no extended jet emission, except for one knot about 1.4" from the quasar. The high X-ray to radio luminosity ratio for this source appears consistent with the $\propto (1+z)^{4}$ amplification expected from the inverse Compton radiative model. This serendipitous discovery may signal the existence of an entire population of similar systems with bright X-ray and faint radio jets at high redshift, a selection bias which must be accounted for when drawing any conclusions about the redshift evolution of jet properties and indeed about the cosmological evolution of supermassive black holes and active galactic nuclei in general

Substructures in the core of Abell 2319

We analysed the deep archival Chandra observations of the high-temperature galaxy cluster Abell 2319 to investigate the prominent cold front in its core. The main sharp arc of the front shows wiggles, or variations of the radius of the density jump along the arc. At the southern end of the arc is a feature that resembles a Kelvin-Helmholtz (KH) eddy, beyond which the sharp front dissolves. These features suggest that KH instabilities develop at the front. Under this assumption, we can place an upper limit on the ICM viscosity that is several times below the isotropic Spitzer value. Other features include a split of the cold front at its northern edge, which may be another KH eddy. There is a small pocket of hot, less-dense gas inside the cold front, which may indicate a `hole' in the front's magnetic insulation layer that lets the heat from the outer gas to penetrate inside the front. Finally, a large concave brightness feature southwest of the cluster core can be caused by the gasdynamic instabilities. We speculate that it can also be an inner boundary of a giant AGN bubble, similar to that in Ophiuchus. If the latter interpretation is supported by better radio data, this could be a remnant of another extremely powerful AGN outburst.Comment: Accepted for publication in MNRA

Deep Chandra observation and numerical studies of the nearest cluster cold front in the sky

We present the results of a very deep (500 ks) Chandra observation, along with tailored numerical simulations, of the nearest, best resolved cluster cold front in the sky, which lies 90 kpc (19 arcmin) to the north-west of M 87. The northern part of the front appears the sharpest, with a width smaller than 2.5 kpc (1.5 Coulomb mean free paths; at 99 per cent confidence). Everywhere along the front, the temperature discontinuity is narrower than 4–8 kpc and the metallicity gradient is narrower than 6 kpc, indicating that diffusion, conduction and mixing are suppressed across the interface. Such transport processes can be naturally suppressed by magnetic fields aligned with the cold front. Interestingly, comparison to magnetohydrodynamic simulations indicates that in order to maintain the observed sharp density and temperature discontinuities, conduction must also be suppressed along the magnetic field lines. However, the northwestern part of the cold front is observed to have a non-zero width. While other explanations are possible, the broadening is consistent with the presence of Kelvin–Helmholtz instabilities (KHI) on length-scales of a few kpc. Based on comparison with simulations, the presence of KHI would imply that the effective viscosity of the intracluster medium is suppressed by more than an order of magnitude with respect to the isotropic Spitzer-like temperature dependent viscosity. Underneath the cold front, we observe quasi-linear features that are ∼10 per cent brighter than the surrounding gas and are separated by ∼15 kpc from each other in projection. Comparison to tailored numerical simulations suggests that the observed phenomena may be due to the amplification of magnetic fields by gas sloshing in wide layers below the cold front, where the magnetic pressure reaches ∼5–10 per cent of the thermal pressure, reducing the gas density between the bright features

Downregulation of miR122 by grainyhead like-2 restricts the hepatocytic differentiation potential of adult liver progenitor cells.

肝臓の組織幹細胞は，肝細胞と胆管上皮細胞に分化可能な細胞である．我々は，転写因子 grainyhead like-2 が，microRNA122 の発現を抑制することによって，肝幹細胞の分化能を制御していることを明らかにした